March 19, 2019

IndexCopernicus Iran
Home Page
News
Journals List
Top 100 Journals
Recently Added Journals
Publishers
Top 20 Publishers
IC Iran Committee Members
Local office address

IndexCopernicus International
Home Page
IC Journals Master List
IC Scientists
IC Conferences

 

IndexCopernicus™ Journal Abstract

 
Antiviral effect assay of twenty five species of various medicinal plants families in Iran
HR Monavari, R Hamkar, Z Norooz-Babaei, L Adibi, M Noroozi, A Ziaei
IJMM 2007; 1(2):49-59
ICID: 541594
Article type: Original article
IC™ Value: 3.25
Abstract provided by Publisher
 
Background and Objectives: Medicinal plants have been traditionally used for different kinds of ailments including infectious diseases. There is an increasing need for substances with antiviral activity since the treatment of viral infections with the available antiviral drugs often lead to the problem of viral resistance. There is a need to search for new and more effective antiviral agents, therefore in the present study 25 plants with ethno-medical background from different families were screened for antiviral activity against HSV-1, Adenovirus type 5, Echovirus type 11, Measles virus and Rotavirus. Material and methods: Different parts of the plants collected from Iran were extracted with aqueous solvents to obtain crude extracts. These extracts were screened for their cytotoxicity against Vero, BSC-1, Hep-II and RD cell lines by micro-culture neutral red dye absorption and microscopically follow up for CPE. Antiviral properties of the plant extracts were determined by cytopathic effect inhibition assay and plaque reduction assay. Results: Four plants extract; Nymphea alba, Rhus coriaria L., Chelidonium majus and Terminalia chebula Retz exhibited significant antiviral activity against HSV-1 and adenovirus type 5 at non-toxic concentration. The extracts of Chelidonium majus showed great anti viral activity against HSV-1 and partial activity against adenovirus at higher concentrations. Conclusion: Some of the medicinal plants have shown antiviral activity. Further research is needed to elucidate the active constituents of these plants which may be useful in the development of new and effective antiviral agents. Keywords: Medicinal plants, Antiviral activity, Herpes Simplex virus, Adenovirus

ICID 541594


Related articles
  • in IndexCopernicus™
         Adenovirus [2 related records]
         herpes simplex virus [6 related records]
         antiviral activity [1 related records]
         Medicinal plants [97 related records]




  •